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Analysis of Clinical Characteristics of Stress Response in the Digestive System Caused by Altitude Sickness

Research background; At an altitude of more than 3,000 m in the plateau area, the oxygen is very thin, which can easily lead to adverse reactions that are difficult to adapt to such as hypoxia, cerebral edema, pulmonary edema, gastrointestinal diseases, etc. This adverse reaction is called altitude sickness, which may cause plateau disease to a certain extent. Research purpose; China belongs to mountainous and hilly areas, and there are countless plateau areas in the southwest, and there are many residents with plateau diseases. In highland areas, in order to reduce altitude sickness and other situations, it is very necessary for us to study the mechanism and treatment process of altitude sickness. Research method; This study conducted a statistical analysis from the statistics of altitude sickness patients from Daocheng county-level medical institutions in Ganzi Prefecture, Sichuan Province from 2010 to 2023. Analysis of the clinical characteristics of cerebral edema, pulmonary edema and gastrointestinal diseases due to altitude sickness, and study the mechanism and principle of occurrence. Research results; The plateau area is an environment prone to hypoxia. Such an environment is most prone to pulmonary edema and cerebral edema. In the study, we found that acute plateau reaction can solve the problem by inhalation of oxygen, but clinically, pulmonary edema, cerebral edema, etc., as well as gastrointestinal diseases.

Plateau Reaction, Alpine Disease, Cerebral Edema, Pulmonary Edema, Gastrointestinal Disease, Blood Oxygen Saturation

APA Style

Liu Yanxi, Liu Chao. (2023). Analysis of Clinical Characteristics of Stress Response in the Digestive System Caused by Altitude Sickness. Clinical Medicine Research, 12(5), 91-94.

ACS Style

Liu Yanxi; Liu Chao. Analysis of Clinical Characteristics of Stress Response in the Digestive System Caused by Altitude Sickness. Clin. Med. Res. 2023, 12(5), 91-94. doi: 10.11648/j.cmr.20231205.11

AMA Style

Liu Yanxi, Liu Chao. Analysis of Clinical Characteristics of Stress Response in the Digestive System Caused by Altitude Sickness. Clin Med Res. 2023;12(5):91-94. doi: 10.11648/j.cmr.20231205.11

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

1. Li Qian. Exploration of the molecular mechanism of plateau disease [J]. Hubei Animal Husbandry and Veterinary, 2020, 41 (3): 7-9.
2. Alimille Yerjiang, Ilyar Nigati, Zhang Xiangyang, Dilinur Maimaiiti. Brief discussion on the development mechanism of acute plateau disease and the latest research progress in prevention and treatment [J]. Advances in clinical medicine, 2023, 13 (2): 2620-2626.
3. Ma Jinju, Cang Baocheng, Yue Wei, Lou Yunxiao, Chen Tao, Mao Xuechao, Sun Qingguo, Chen Yuanyuan, Ding Zailiang, Yang Ming, Sun Lidong, Xie Jun. The influence of rapid plateau on the function of human circulatory system [J]. Journal of Zhengzhou University (Medical Edition), 2020, 55 (6): 810-815.
4. Ma Rong, Rong Guanghong. Effect of hypoxia environment of the rapid plateau on the intestinal mucosal barrier [J]. Advances in clinical medicine, 2022, 12 (11): 9886-9890.
5. Liu Kaifeng, Yang Han, Zuo Xiaoqing, etc. Exploration of plateau emergency oxygen supply guarantee model based on liquid oxygen storage and supply [J]. China Emergency Rescue, 2022 (5): 53-58.
6. Huo Ruiqing, Tian Junbiao, Zhao Minhan, etc. Effect of turbidity detoxification and blood circulation prescription on LPS and TLR4/NF-κB signaling pathways in rats with cerebral ischemia-reperfusion injury [J]. Chinese Journal of Immunology, 2022, 38 (11): 1317-1323+1332.
7. Duan Kunkun, Wang Yafeng. Research status of intestinal microecological disorders and prevention and treatment in plateau hypoxia environment [J]. Chinese Journal of Plateau Medicine and Biology, 2021, 42 (2): 142-144.
8. Li Yue, Xiang Ethics, Duan Jiaxiang, Gu Jianteng, Yi Bin, Lu Kaizhi, Chen Ka, Mi Mantian, Li Peng, Ying Jiaolin. Distal limb ischemia pretreatment relieves changes in blood circulation caused by rapid plateau [J]. Journal of Army Medical University, 2022, 44 (3): 203-209.
9. Lu Mingzhi, Ning Bin, Hu Ying. Clinical significance of central venous oxygen saturation monitoring in patients with chronic heart failure [J]. Electronic Journal of Cardiovascular Diseases of Traditional Chinese and Western Medicine, 2020, 8 (8): 55-59.
10. Wang Chi, Wang Chengbin. Research progress on the diagnosis and predictors of acute altitude sickness [J/CD]. Journal of Clinical Testing (electronic version), 2021, 3 (4): 717-723.
11. Li Ming, Zhang Jihang, Bian Shizhu, etc. Study on the relationship between oxygen transport volume and its compensation factors and acute altitude sickness [J]. PLA Medical Journal, 2020, 38 (3): 245-248.
12. Gao Yuqi, Huang Yan. Inflammatory reaction and altitude sickness [J]. Journal of the Third Military Medical University, 2021, 38 (3): 215-219.
13. Qi Shenggui, Wu Tianyi. Diagnostic criteria and related research of chronic plateau disease [J]. Journal of Plateau Medicine, 2023, 25 (4): 1-10.
14. Liu B, Huang H, Wang SX, et al. Physiological adjustments and circulatin microRNA reprogramming are involved in early acclimatization to high altitude in Chinese han males [J]. Front Physiol, 2020 (7): 601.
15. Arieli R, Vitenstein A, Peled E. Acclimation to hypoxia does not improve hypoxic survival of the immature pig in confined atmosphere [J]. Mil Med, 2020, 173 (1): 107-111.
16. Hartmann G, Tschop M, Fischer R, et al. High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein [J]. Cytokine, 2022, 12 (3): 246-252.
17. Prabhakar NR, Semenza GL. Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2 [J]. Physiol Rev, 2022, 92 (3): 967-1003.
18. Xie SW, Liu C, Gao YX, et al. The study of prevalence rate, and clinical characteristics of high altitude deterioration [J]. Eur Rev Med Pharmacol Sci, 2021, 19 (18): 3444-3449.