Clinical Medicine Research

Special Issue

Epigenetic Modification of Essential Hypertension Gene and Gene Therapy

  • Submission Deadline: Dec. 01, 2022
  • Status: Submission Closed
  • Lead Guest Editor: Zhi xiong Zhong
About This Special Issue
Essential hypertension is a multi-gene hereditary disease which is affected by heredity, environment and nutrition. The study of essential hypertension should not be limited to the risk factors of hypertension: high sodium diet, alcoholism, smoking, obesity, diabetes, mental stress, gene polymorphism, but more attention should be paid to epigenetics of essential hypertension. Why does the environment influence the selective expression of essential hypertension genes? Epigenetic modification of hypertension plays a big role. And the effect may be passed down to the next generation. Epigenetics of essential hypertension include DNA methylation, histone modification, non-coding RNA, etc. The goal of this special issue is to gather the latest research results of hypertension gene research, hypertension epigenetics, and hypertension gene therapy, and find the treatment plan for essential hypertension according to the gene and gene expression.


  1. Essential Hypertension
  2. Hypertension Gene
  3. Epigenetics of Hypertension Genes
  4. Epigenetic Modification
  5. Hypertension Gene Therapy
  6. Hypertension Gene Polymorphism
Lead Guest Editor
  • Zhi xiong Zhong

    The First People's Hospital of Shaoguan, Shao Guan, China

Guest Editors
  • Zhi chao Qiu

    The First People's Hospital of Shaoguan, Shao Guan, China

  • Long Zeng

    Chenzhou First People's Hospital, Chen zhou, China

  • Xue wen Wang

    Renmin hospital of Wuhan University, Wu Han, China

  • Chao Jun Wei

    Department of Cardiovascular Medicine, Affiliated Hospital of Guizhou Medical University, Gui yang, China

  • Juan Tan

    Bazhong Central Hospital, Ba Zhong, China

  • Luo Chao Zhang

    Xinxiang Central Hospital, Xin Xiang, China

Published Articles
  • A Case of Wellens Syndrome Combined with De Winter Syndrome

    Zhixiong Zhong , JueTong Chen , Ning Xu , Zhichao Qiu , Jianyong Zhang , Guibin Liu , Fanchao Zeng

    Issue: Volume 11, Issue 3, May 2022
    Pages: 36-41
    Received: Apr. 03, 2022
    Accepted: May 06, 2022
    Published: May 12, 2022
    DOI: 10.11648/j.cmr.20221103.11
    Abstract: This paper reports a typical case of Wellens syndrome combined with De Winter syndrome. The male patient was admitted with "one day chest pain". He is 64 years old. He had chest pain without obvious inducement. Preliminary diagnosis: coronary heart disease unstable angina pectoris. The Electrocardiogram of this case is typical of Wellens syndrome. ... Show More